Searchable abstracts of presentations at key conferences in endocrinology

ea0098b27 | Basic Science | NANETS2023

Development of GEP-NEN patient derived organoids for therapy screening

Forsythe Steven D. , Madigan James P. , Andrews Stephen , del Rivero Jaydira , Hernandez Jonathan M. , Nilubol Naris , Sadowski Samira M.

Background: Gastroenteropancreatic Neuroendocrine Neoplasms (GEP-NENs) are a rare subset of cancers which nevertheless are a rising health burden. Development of new therapies suffers from several bottlenecks, including low patient accrual and poor understanding of tumor characteristics. Patient tumor organoids (PTOs) are a novel model capable of improving screening of patient tissue in an accurate, standardized, and high-throughput capacity. In this study, we utilized patient...